Biología Molecular


Datos Curriculares

Datos Curriculares

Dr. Ángel Gabriel Alpuche Solís

Coordinador de Lanbama

Miembro del SNI. Nivel 2

División de Biología Molecular



+52 (444) 8342055




+52 (444) 8342000

Selección de artículos de investigación

Publicaciones en el Science Citation Index

1.- Moreno-Perlin TM, Alpuche-Solís AG, Badano EI, Etchebehere C, Ceis LB "Toward a solution for acid mine drainage treatment: role of electron donors in sulfate reduction at low pH". GEOMICROBIOLOGY JOURNAL . 2019;

36 (9) : 837-843

2.- Fragoso-Serrano Mabel, Ortíz-Pastrana Naytzé, Luna-Cruz Norma, Toscano Rubén A., Alpuche-Solís Angel, Ortega, Alfredo, Bautista Elihú "Amarisolide F, an acylated diterpenoid glucoside and related terpenoids from Salvia amarissima". JOURNAL OF NATURAL PRODUCTS . 2018;

82 : 631-635

3.- Martínez-Castro, E., Jarquin-Gálvez, R., Alpuche-Solís, A.G., Vallejo-Pérez, M.R. Colli-Mull, J.G. and Lara-Ávila, J.P. "Bacterial wilt and canker of tomato: fundamentals of a complex biological system". EUPHYTICA . 2018;

(en impresión (aceptado))

4.- Ortega-Rivera, O.A., Quintanar, J.L., Del Toro-Arreola, S., Alpuche-Solis, A.G., Esparza-Araiza, M.J., Salinas, E. "Antitumor and immunostimulatory activities of a genotype V recombinant attenuated veterinary Newcastle disease virus vaccine". ONCOLOGY LETTERS . 2017;

15 : 1246-1254

5.- Domínguez-Pérez, R.A., Loyola-Rodríguez, J.P., Abud-Mendoza, C., Alpuche-Solis, A.G., Ayala-Herrera, J.L., Martínez-Martínez, R.E. "Association of cytokines polymorphisms with chronic peridontitis and rheumatoid arthritis in a Mexican population". ACTA ODONTOLOGICA SCANDINAVICA . 2017;

75 : 243-248

6.- Gutiérrez-Ortega, A., Rivera, I., Cruz-Franco, S., Gutiérrez-Mora, A., Alpuche-Solís, A.G., Sánchez-Hernández, C., Horchani, H., Sandoval, G. "Identification, cloning and expression of a new GDSL lipase from Carica papaya. ". PROCESS BIOCHEMISTRY . 2017;

55 : 70-76

7.- Gaytán-Luna, D.E., Ochoa Alfaro, A.E., Rocha-Uribe, A., Rosales-Mendoza, S., Pérez-Martínez, A.S., Alpuche-Solís, A.G., Soria-Guerra, R.E. "Changes in light wavelength influence lipid accumulation in the green alga Chlamydomonas reinhardtii". BIOTECHNOLOGY PROGRESS . 2016;

32 : 1404-14011

8.- Hernández-Camacho, S., Pérez-Molphe-Balch, E., Alpuche-Solís, A.G., Morales-Domínguez, J.F. "Identification and evolutionary relationships of partial gene sequences from dehydrin group in three species of cacti". PHYTON - INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY . 2016;

86 : 151-162

9.- Palomeque-Carlín, A., Tafoya, F. , Alpuche Solís, A.G., Pérez- Molphe-Balch E. "Effect of different culture media and conditions in biomass production of hairyroot cultures in six Mexican cacti species. ". IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT . 2015;

51 : 332-339

10.- Ortega-Berlanga B., Musiychuk, K., Shoji, Y., Chichester, J.A., Yusibov, V. Patiño-Rodríguez, O., Noyola, D.E., Alpuche-Solís, A.G. "Engineering and expression of a RhoA peptide against respiratory syncytial virus infection in plants". PLANTA . 2015;

243 : 451-458

11.- Esparza-Araiza, M.J., Bañuelos-Hernández, B., Argüello-Astorga, G.R., Lara-Ávila, J.P., Goodwin, P.H., Isordia-Jasso, M.I., Castillo-Collazo, R., Rougon-Cardoso, A., Alpuche-Solís, A.G. "Evaluation of a SUMO E2 conjugating enzyme involved in resistance to Clavibacter michiganensis subsp. michiganensis in Solanum peruvianum, through a tomato mottle virus VIGS assay". FRONTIERS IN PLANT SCIENCE . 2015;


12.- Márquez-Escobar, V.A., Tirado-Mendoza, R., Noyola D.E., Gutiérrez-Ortega, A. , Alpuche-Solís, A.G. "HRA2pl peptide: a fusion inhibitor for human metapneumovirus produced in tobacco plants by transient transformation". PLANTA . 2015;

242 : 69-76

13.- Montoya, L., Celis, L.B., Gallegos-Garcia, M., Razo-Flores, E., Alpuche-Solís, A. "Consortium diversity of a sulfate-reducing biofilm developed at acidic pH influent conditions in a down-flow fluidized bed reactor". ENGINEERING IN LIFE SCIENCES . 2013;

13 : 302-311

14.- Patiño-Rodríguez, O., Ortega-Berlanga, B., Llamas-González, Y.Y., Flores-Valdez, M.A., Herrera-Día, A., Montes de Oca-Luna, R., Korban, S.S., Alpuche-Solís, A.G. "Transient expression and characterization of the antimicrobial peptide Protegrin-1 in Nicotiana tabacum for control of bacterial and fungal mammalian pathogens". PLANT CELL TISSUE AND ORGAN CULTURE . 2013;

115 : 99-106

15.- Rubio-Infante, N., Govea-Alonso, D.O., Alpuche-Solís, A.G., García- Hernández, A.L., Soria-Guerra, R.E., Paz-Maldonado, L.M.T., Ilhuicatzi-Alvarado, D., Varona-Santos, J.T., Verdín-Terán, L., Korban, S.S., Moreno-Fierros, L. y Rosales-Mendoza, S. "A chloroplast-derived C4V3 polypeptide from human immunodeficiency virus (HIV) is orally immunogenic in mice.". PLANT MOLECULAR BIOLOGY . 2012;

78 : 337-349

16.- Montoya, L., Celis, L.B., Razo-Flores, E. y Alpuche-Solís, A.G. "Distribution of CO2 fixation and acetate mineralization pathways in microorganisms from extremophilic anaerobic biotopes. A review.". EXTREMOPHILES . 2012;

16 : 805-817

17.- Cervantes, FJ, Mancilla, AR, Ríos-del Toro, EE, Alpuche-Solis, AG & Montoya-Lorenzana, L. "Anaerobic benzene oxidation by enriched inocula with humic acids as terminal electron acceptors". JOURNAL OF HAZARDOUS MATERIALS . 2011;

195 : 201-207

18.- Lara-Ávila, J.P., Isordia-Jasso, M.I., Castillo-Collazo, R., Simpson, J., y Alpuche-Solís, A.G. "Gene expression analysis during interaction of tomato and related wild species with Clavibacter michiganensis subsp. michiganensis". PLANT MOLECULAR BIOLOGY REPORTER . 2011;

30(2) : 498-511.

19.- Rosales-Mendoza, S., Soria-Guerra, R.E., Moreno-Fierros, L., Govea-Alonso, D.O., Herrera-Díaz, A., Korban, S.S. y Alpuche-Solís, A.G. "Immunogenicity of nuclear encoded LTB:ST fusion protein from Escherichia coli expressed in tobacco plants". PLANT CELL REPORTS . 2011;

30(6) : 1145-1152

20.- Martínez-González, L., Rosales-Mendoza, S., Soria-Guerra, R.E., Moreno-Fierros, L., López-Revilla, R., Korban, S.S., Guevara-Arauza, J.C. y Alpuche-Solís, A.G. "Oral immunization with a lettuce-derived Escherichia coli heat-labile toxin B subunit induces neutralizing antibodies in mice.". PLANT CELL TISSUE AND ORGAN CULTURE . 2011;

107 : 441-449

21.- Soria-Guerra R.E., Rosales-Mendoza, S., Moreno-Fierros, L., López-Revilla, R., y Alpuche-Solís, A.G. "Oral immunogenicity of tomato-derived sDPT polypeptide containing Corynebacterium diphtheriae, Bordetella pertussis and Clostridium tetani exotoxin epitopes". PLANT CELL REPORTS . 2011;

30(3) : 417-424.

22.- Rosales-Mendoza, S., Soria-Guerra, R.E., Moreno-Fierros, L., Han Y., Alpuche-Solis, A.G., y Korban S.S. "Transgenic carrot tap roots expressing an inmmunogenic F1-V fusión protein from Yersinia pestis are immunogenic in mice". JOURNAL OF PLANT PHYSIOLOGY . 2011;

168 : 174-180

23.- Rosales-Mendoza, S., Soria-Guerra, R.E., Moreno-Fierros, L., Alpuche-Solis, A.G., Martínez-González, L., y Korban S.S. "Expression of an immunogenic F1-V fusion protein in lettuce as a plant-based vaccine against plague". PLANTA . 2010;

232(2) : 409-416

24.- Celis, L.B., Villa-Gómez, D., Alpuche-Solís, A.G., Ortega-Morales, B.O., Razo-Flores, E. "Characterization of sulfate-reducing bacteria dominated surface communities during start-up of a down-flow fluidized bed reactor". JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY . 2009;

36(1) : 111-121

25.- Soria-Guerra, R.E.*, Alpuche-Solís, A.G.*, Rosales-Mendoza, S., Moreno-Fierros, L., Bendik E.M., Martínez-González, L. y Korban, S.S. "Expression of a multi-epitope DPT fusion protein in transplastomic tobacco plants retains both antigenicity and immunogenicity of all three components of the functional oligomer.". PLANTA . 2009;

229(6) : 1293-1302

26.- Rosales-Mendoza, S.*, Alpuche-Solís, A.*, Soria-Guerra, R, Moreno-Fierros, L., Martínez-González, L., Herrera-Díaz, A., y Korban, S.S. "Expression of an Escherichia coli antigenic fusion protein comprising the heat labile toxin B subunit and the heat stable toxin and its assembly as a functional oligomer in transplastomic tobacco plan". PLANT JOURNAL . 2009;

57 : 45-54

27.- Steve Smith, Tulio Arredondo , Martin Aguiar , Elisabeth Huber-Sannwald , Angel Alpuche , Armando Aguado , Oscar Grageda , Kandres Halbrook , Cecilia Bottini "Fine-scale Spatial Genetic Structure in Perennial Grasses in Three Environments". RANGELAND ECOLOGY & MANAGEMENT . 2009;

62(4) : 356-363

28.- Beristain-Cardoso, R., Texier, A-C, Alpuche-Solís, A., Gómez, J., Razo-Flores, E. "Phenol and sulfide oxidation in a denitrifying biofilm reactor and its microbial community analysis". PROCESS BIOCHEMISTRY . 2009;

44(1) : 23-28

29.- Gómez-Villa, R.J., Comas-García, A., Rojas-López, V., Pérez-González, L.F., Sánchez-Alvarado, J., Salazar-Zaragoza, R., Ruiz-González, J.M., Alpuche-Solís, A.G., y Noyola-Cherpitel, D.E. "Effect on an infection control program on the frequency of nosocomial viral respiratory infections". INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY . 2008;

29(6) : 556-558

30.- Davila-Pérez, C., Amano, A., Alpuche-Solís, A.G., Patiño-Marín, N., Pontigo-Loyola, A.P., Hamada, S. y Loyola-Rodríguez, J.P. "Distribution of genotypes of Porphyromonas gingivalis in type 2 diabetic patients with periodontitis in Mexico. ". JOURNAL OF CLINICAL PERIODONTOLOGY . 2007;

34(1) : 25-30 Número de citas: 1

31.- Sergio Rosales-Mendoza, R E Soria-Guerra, M Tde J Olivera-Flores, R López-Revilla, G R Arguello-Astorga, J F Jiménez-Bremont, R F García-de La Cruz, J P Loyola-Rodríguez, and Ángel G "EXPRESSION OF Escherichia coli HEAT-LABILE ENTEROTOXIN B SUBUNIT (LTB) IN CARROT (Daucus carota L.)". PLANT CELL REPORTS . 2007;

26(7) : 969-976 Número de citas: 3

32.- Flores-Benítez, S., Jiménez-Bremont, J.F., Rosales-Mendoza, S., Argüello-Astorga, G.R., Castillo-Collazo, R. y Alpuche-Solís, A.G. "Genetic transformation of Agave salmiana by Agrobacterium tumefaciens and particle bombardment. ". PLANT CELL TISSUE AND ORGAN CULTURE . 2007;

91(3) : 215-224

33.- Rosales-Mendoza, S., Soria-Guerra, R, López-Revilla, R., Moreno-Fierros, L., y Alpuche-Solís, A.G. "Ingestion of transgenic carrots expressing the Escherichia coli heat-labile enterotoxin B subunit protects mice against cholera toxin challenge. ". PLANT CELL REPORTS . 2007;

27 : 79-84

34.- Ruth Elena Soria-Guerra, Sergio Rosales-Mendoza, Crisóforo Márquez-Mercado , Rubén López-Revilla, Rosalba Castillo-Collazo and Ángel G. Alpuche-Solís, "Transgenic tomatoes express an antigenic polypeptide containing epitopes of the diphtheria, pertussis and tetanus exotoxins, encoded by a synthetic gene". PLANT CELL REPORTS . 2007;

26(7) : 961-968 Número de citas: 1

35.- J. F. JIMÉNEZ-BREMONT1, E. HERNÁNDEZ-LUCERO, A. G. ALPUCHE-SOLÍS, S. CASAS-FLORES and A. P. BARBA DE LA ROSA "Differential distribution of transcripts from genes involved in polyamine biosynthesis in bean plants". BIOLOGIA PLANTARUM . 2006;

50 : 551-558

36.- Margarita Rodríguez-Kessler*, Angel G. Alpuche-Solís*, Oscar A. Ruiz** and Juan F. Jiménez-Bremont*+ "Effect of salt stress on the regulation of maize (Zea mays L.) genes involved in polyamine biosynthesis". PLANT GROWTH REGULATION . 2006;

48 : 175-185

37.- Schneider, R., Fernández, F.J., Aguilar, M.B., Guerrero-Legarreta, I. , Alpuche-Solís, A.G. y Ponce-Alquicira, E. "Partial characterization of a class II pediocin produced by Pediococus parvulus 133 strain isolated from meat (mexican ". FOOD CONTROL . 2006;

17(11) : 909-915 Número de citas: 3

38.- Noyola, D.E., Alpuche-Solís, A.G., Herrera-Díaz, A., Soria-Guerra, R.E., Sánchez-Alvarado, J., López-Revilla, R.H. "Human metapneumovirus infections in Mexico: Epidemiological and clinical characteristics.". JOURNAL OF MEDICAL MICROBIOLOGY . 2005;

54 : 969-974 Número de citas: 15

39.- Griffiths, A., Barry, C., Alpuche-Solis, A.G. y Grierson, D. "Ethylene and developmental signals regulate expression of lipoxygenase genes during tomato fruit rip". JOURNAL OF EXPERIMENTAL BOTANY . 1999;

50 (335) : 793-798 Número de citas: 33

40.- Hamilton, A.J., Brown, S., Yuanhai, H., Ishizuka, M., Lowe, A., Alpuche-Solis, A.G., y Grierson, D. "A Transgene with repeated DNA causes high frequency, post-transcriptional suppression of ACC-oxid". PLANT JOURNAL . 1998;

15 (6) : 737-746 Número de citas: 76

41.- Hackett, R.M., C. Barry, C., Alpuche-Solís, A.G., Wilson, I. Foote, H., Santalla, M., Oh, S.A. y Grierson, D "Control of ripening and senescence in tomato. Society for Experimental Biology, Annual Meeting". JOURNAL OF EXPERIMENTAL BOTANY . 1998;

42.- Alpuche-Solís, A.G. y Paredes-López, O "Assessment of glucosinolates in broccoli by three different methodologies". JOURNAL OF FOOD BIOCHEMISTRY . 1993;

16 : 265-275

Publicaciones en otros índices internacionales

1.- Solis-Rodríguez, M., Alpuche-Solís, Á.G., Tirado-Mendoza, R.G. "Metapneumovirus humano: Epidemiología y posibles tratamientos profilácticos. ". Revista de la Facultad de Medicina de la UNAM . 2020;

(en impresión (aceptado))

2.- Lara-Ávila J.P. Alpuche-Solís, A.G. "Análisis de la diversidad genética de agaves mezcaleros del centro de México". Revista Fitotecnia Mexicana . 2016;

39 : 323-330

3.- Reyes-Silva, A.I., Núñez-Palenius, H.G., Hernández-Guzmán, G., Alpuche-Solís, A.G., Garcidueñas-Piña, C., Morales-Domínguez, J.F. "ADNc relacionados con la maduración del fruto de guayaba (Psidium guajava l.): caracterización y análisis de expresión. Rripening-related cdnas in guava fruit (Psidium guajava l.): characterization an". Revista Fitotecnia Mexicana . 2013;

36(2) : 117-125

4.- Morales-Domínguez, J.F., Soria-Guerra, R.E., Alpuche-Solís, A.G., Garcidueñas-Piña, C.E. "Expresión de una alfa-expansina implicada en la maduración del fruto de guayaba (Psidium guajava l.). Expression of an alpha-expansin involved in guava (Psidium guajava l.) fruit ripening. ". Investigación y Ciencia de la Universidad Autónoma de Aguascalientes . 2013;

58 : 5-11

5.- Gregorio-Jorge J, Bernal-Alcocer A, Banuelos-Hernandez B, Alpuche-Solis AG, Hernandez-Zepeda C, Moreno-Valenzuela O, Frias-Trevino G, Arguello-Astorga GR. "Analysis of a new strain of Euphorbia mosaic virus with distinct replication specificity unveils a lineage of begomoviruses with short Rep sequences in the DNA-B intergenic region.". . 2010;

7(1) : 275

6.- Loyola-Rodriguez, J.P., Martínez-Martínez, R.E., Flores-Ferreyra, B.I., Patiño-Marín, N., Alpuche-Solís, A.G., Reyes-Macías, J.F. "Distribution of Streptococcus mutans and Streptococcus sobrinus in saliva of mexican preschool caries-free and caries-active children by microbial and molecular (PCR) assays.". The Journal of Clinical Pediatric Dentistry . 2008;

32(2) : 123-128

7.- Domínguez-Rosales, M.S., Alpuche-Solís, A.G., Vasco-Mendez, N.L., Pérez-Molphe-Balch, E. "Efecto de citocininas en la propagación in vitro de especies mexicanas de Agave". Revista Fitotecnia Mexicana. . 2008;

31(4) : 327-322

8.- Azuara-Hernández, L., Silos-Espino, E., Perales-Segovia, C., Gómez-Leyva, J.F., Alpuche-Solís, A.G. y Macias-Valdez, L.M. "Identification by morphological and genetic characterization of a collection of garlic cultivate in Mexico Central-North region". Phyton: International Journal of Experimental Botany. . 2008;

77 : 81-91

Publicaciones en revistas no indizadas

1.-Garcidueñas-Piña, C., Alpuche-Solís, A,G., Gutiérrez-Campos, R. y Morales-Domínguez, J.F. "Expresión de una alfa-expansina de guayaba (Psidium guajava L) en sistemas bacterianos.". Scientiae Naturae . 2007;

IX(2) : 23-33

2.-Ocaña-Camacho, R., Alpuche-Solís. A.G. y Pardes-López, O "Potencial actual de la biotecnología para la producción de hongos comestibles empleando desperdicios". Acta Universitaria . 1994;